The effects analysis of two neonicotinoid insecticides on in vitro maturation of porcine oocytes using hanging drop monoculture method

Sadamasa Ishikawa, Kou Hiraga, Yuuki Hiradate, Kentaro Tanemura

    Research output: Contribution to journalArticlepeer-review

    1 Citation (Scopus)

    Abstract

    Acetamiprid (ACE) and imidacroprid (IMI) are known neonicotinoid insecticides with strong affinities for the insect-selective nicotinic acetylcholine receptor. These provide insect control by hyperstimulating insect nerves and are used for agricultural pest management. However, it has also been reported that ACE and IMI affect mammalian reproductive function. We determined the effects of ACE and IMI on the in vitro maturation of porcine oocytes. Significant decreases in nuclear maturation rates were observed in the ACE or IMIexposed groups. Also, in matured oocytes from the ACE or IMI-exposed groups, irregular chromosomes were observed. Our results suggest that ACE and IMI exposure was detrimental to porcine oocytes and the extent of the effects depends on the concentration of exposure.

    Original languageEnglish
    Pages (from-to)725-728
    Number of pages4
    JournalJournal of Veterinary Medical Science
    Volume77
    Issue number6
    DOIs
    Publication statusPublished - 2015 Jul 1

    Keywords

    • Hanging drop
    • In vitro maturation (IVM)
    • Neonicotinoid
    • Porcine oocyte

    ASJC Scopus subject areas

    • veterinary(all)

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