The consumption of a structured triacylglycerol containing behenic and oleic acids increases fecal fat excretion in humans

Makiko Kojima, Toshiharu Arishima, Ryoma Shimizu, Mitsutaka Kohno, Haruyasu Kida, Motohiko Hirotsuka, Ikuo Ikeda

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

We examined the fecal fat excretion of mildly hypertriacylglycerolemic subjects who ingested soft cookies containing 1(3)-behenoyl-2,3(1)-dioleoyl-rac-glycerol (BOO) for 7 days. The subjects included 14 healthy men (average age; 44.9 ± 1.7) whose fasting plasma triacylglycerol level ranged from 150 to 250 mg/dL. Every day for 7 days, the subjects ate 5 soft cookies containing margarine with the BOO-rich experimental oil (BOO intake, 2.46 g/day). The placebo group ate soft cookies containing margarine without BOO. This study was a randomized double-blind, placebo-controlled, crossover study. Feces were collected for 3 days prior to the end of the treatment period, and fecal fat and fatty acid composition were determined. The fecal wet weight was significantly increased in BOO group compared with that in the placebo group. Moreover, fecal fat and fatty acid level were significantly higher in the BOO group than in the placebo group. There were no significant differences in the fecal fatty acid composition of the BOO and placebo groups. These results suggest that dietary BOO increases fecal excretion of dietary fat in humans. However, BOO does not increase the excretion of specific fatty acids; it increases the excretion of all fatty acids of dietary origin, which may lead to lower and delay intestinal absorption of dietary fat.

Original languageEnglish
Pages (from-to)997-1001
Number of pages5
JournalJournal of oleo science
Volume62
Issue number12
DOIs
Publication statusPublished - 2013 Dec 4

Keywords

  • Absorption
  • Behenic acid
  • Excretion
  • Fecal fatty acid
  • Lipase

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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