The comparison of drug susceptibility of antituberculous agents against colonizing M. intracellulare and infectious M. intracellulare

S. Maesaki, Y. Higashiyama, K. Mitsutake, H. Matsuda, H. Yamada, H. Sugiyama, M. Kaku, H. Koga, S. Kohno, K. Hara

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Abstract

The susceptibility of antituberculous agents against colonized M. intracellulare which were isolated from patients with pulmonary disease and infectious M. intracellulare (pathogens) isolated from atypical mycobacterial culture was investigated. Aminoglycosides were more potent against colonized organisms than against pathogens. Isoniazid, ethambutol and rifampicin showed less potent antimicrobial activity against both colonized organism and pathogens as compared to aminoglycosides. On the contrary susceptibility of cycloserine against colonized organisms was as potent as against pathogens.

Original languageEnglish
Pages (from-to)503-505
Number of pages3
JournalKekkaku : [Tuberculosis]
Volume66
Issue number7
Publication statusPublished - 1991 Jul

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases

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    Maesaki, S., Higashiyama, Y., Mitsutake, K., Matsuda, H., Yamada, H., Sugiyama, H., Kaku, M., Koga, H., Kohno, S., & Hara, K. (1991). The comparison of drug susceptibility of antituberculous agents against colonizing M. intracellulare and infectious M. intracellulare. Kekkaku : [Tuberculosis], 66(7), 503-505.