The chemical structure of a tetrasaccharide containing N-acetylglucosamine obtained from bovine colostrum κ-casein

Tadao Saito, Takatoshi Itoh, Susumu Adachi

    Research output: Contribution to journalArticlepeer-review

    24 Citations (Scopus)

    Abstract

    A tetrasaccharide consisting of D-galactose, N-acetylneuraminic acid, N-acetylglucosamine and N-acetylgalactosaminitol (1 : 1 : 1 : 1) was obtained from bovine colostrum κ-casein. It is the main carbohydrate portion of a caseinoglycopeptide formed by alkaline borohydride treatment. The carbohydrate sequence was analyzed by enzymatic and chemical methods and by mass spectrometry, and was shown to be N-acetylglucosaminyl-β-1-3-galactosyl-β-1-3-[N-acetylneuraminyl-α-2-6-]-N-acetylgalactosaminitol.

    Original languageEnglish
    Pages (from-to)487-494
    Number of pages8
    JournalBBA - General Subjects
    Volume673
    Issue numberC
    DOIs
    Publication statusPublished - 1981

    Keywords

    • (Bovine colostrum)
    • Carbohydrate sequence
    • Caseinoglycopeptide
    • κ-Casein

    ASJC Scopus subject areas

    • Biophysics
    • Biochemistry
    • Molecular Biology

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