The association between orthostatic increase in pulse pressure and ischemic heart disease

Munenori Takata, Eisuke Amiya, Masafumi Watanabe, Namie Yamada, Aya Watanabe, Shuichi Kawarasaki, Atsuko Ozeki, Tomoko Nakao, Yumiko Hosoya, Jiro Ando, Issei Komuro

Research output: Contribution to journalArticle

Abstract

The clinical meaning of changes in PP with posture remains unclear. We performed treadmill exercise testing on 144 subjects to diagnose ischemic heart disease, and measured the PPs in the supine and standing positions. The differences in the two PPs ranged between-35 and 45 mmHg. Eleven subjects were diagnosed with significant coronary ischemia. The differences in the PPs were significantly increased, and PP in the standing position was significantly elevated in these subjects. A large difference in the PPs in the standing and supine positions was associated with significant coronary ischemia, independent of significant covariables.

Original languageEnglish
Pages (from-to)23-29
Number of pages7
JournalClinical and Experimental Hypertension
Volume38
Issue number1
DOIs
Publication statusPublished - 2016 Jan 2

Keywords

  • Ischemic heart disease
  • orthostatic change
  • pulse pressure

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology

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  • Cite this

    Takata, M., Amiya, E., Watanabe, M., Yamada, N., Watanabe, A., Kawarasaki, S., Ozeki, A., Nakao, T., Hosoya, Y., Ando, J., & Komuro, I. (2016). The association between orthostatic increase in pulse pressure and ischemic heart disease. Clinical and Experimental Hypertension, 38(1), 23-29. https://doi.org/10.3109/10641963.2015.1047948