The arabidopsis voltage-dependent anion channel 2 is required for plant growth

Chika Tateda, Tomonobu Kusano, Yoshihiro Takahashi

    Research output: Contribution to journalArticle

    6 Citations (Scopus)

    Abstract

    The voltage-dependent anion channels (VDACs), known as a major group of outer mitochondrial membrane proteins, are present in all eukaryotic species. In mammalian cells, they have been established as a key player in mitochondrial metabolism and apoptosis regulation. By contrast, little is known about the function of plant VDACs. Recently, we performed functional analysis of all VDAC gene members in Arabidopsis thaliana, and revealed that each AtVDAC member has a specialized function. Especially, in spite of similar subcellular localization and expression profiling of AtVDAC2 and AtVDAC4, both the T-DNA insertion knockout mutants of them, vdac2-2 and vdac4-2, showed severe growth retardation. These results suggest that AtVDAC2 and AtVDAC4 proteins clearly have distinct functions. Here, we introduced the AtVDAC2 gene into the vdac2-2 mutant, and demonstrated that the miniature phenotype of vdac2-2 plant is abolished by AtVDAC2 expression.

    Original languageEnglish
    JournalPlant Signaling and Behavior
    Volume7
    Issue number1
    DOIs
    Publication statusPublished - 2012 Jan 1

    Keywords

    • Arabidopsis thaliana
    • AtVDAC2
    • AtVDAC4
    • Mitochondrial porin signature
    • Plant growth
    • Voltage-dependent anion channel

    ASJC Scopus subject areas

    • Plant Science

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