The acute anorexic effect of liraglutide, a GLP-1 receptor agonist, does not require functional leptin receptor, serotonin, and hypothalamic POMC and CART activities in mice

Katsunori Nonogaki, Takao Kaji

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The acute anorexic effect of liraglutide, a GLP-1 receptor agonist, did not require functional leptin receptor, serotonin, and hypothalamic proopiomelanocortin and cocaine amphetamine regulated transcript activities in mice, although decrease in functional hypothalamic orexin activity might be involved in the acute anorexic effect of liraglutide.

Original languageEnglish
Pages (from-to)186-189
Number of pages4
JournalDiabetes Research and Clinical Practice
Volume120
DOIs
Publication statusPublished - 2016 Oct 1

Keywords

  • 5-HT
  • Food intake
  • GLP-1 receptor
  • Liraglutide
  • Orexin
  • POMC

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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