The accumulation of11C-methionine in cerebral glioma patients studied with PET

M. Kameyama, R. Shirane, J. Itoh, K. Sato, R. Katakura, T. Yoshimoto, J. Hatazawa, M. Itoh, T. Ido

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33 Citations (Scopus)


Fourteen patients with cerebral gliomas were studied with positron emission tomography (PET) using L-[methyl-11C]methionine (11C-MET). Positive images of tumour were obtained in all cases regardless of histological grades. The analysis of differential absorption ratio (DAR) showed the higher accumulation of11C-MET in high grade gliomas than in low grade gliomas. PET study with11C-MET will be of great value not only in delineating the location of gliomas, but also in making a qualitative diagnosis from the view point of the biological properties of gliomas.

Original languageEnglish
Pages (from-to)8-12
Number of pages5
JournalActa neurochirurgica
Issue number1-2
Publication statusPublished - 1990 Mar 1
Externally publishedYes


  • Amino acid metabolism
  • C-methionine
  • PET
  • brain tumour
  • cerebral glioma

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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