The 3D position estimation of neurons in the hippocampus based on the multi-site multi-unit recordings with silicon tetrodes

Takashi Kubo, Norihiro Katayama, Akihiro Karashima, Mitsuyuki Nakao

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Citations (Scopus)

Abstract

The mechanical strain of the neural tissue induced by the implant of neuronal electrode is one of the important factors responsible for the quality and performance of extracellular recording of neuronal activities in the brain because the mechanical strain could kill or inactivate the neurons. In order to evaluate the effect of the implant of neural electrode, we propose a method to estimate the three-dimensional distribution of electrophysiologically active neurons near the electrode based on the multi-site multi-unit recording data. The spatial distribution of the active neurons emerges the region in the neural tissue that could be killed or inactivated by the implant of the electrode. The proposed method will be useful for the in situ assessment of the neural electrode implanted in the brain.

Original languageEnglish
Title of host publicationProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
Pages5021-5024
Number of pages4
Publication statusPublished - 2008 Dec 1
Event30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, Canada
Duration: 2008 Aug 202008 Aug 25

Publication series

NameProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"

Other

Other30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
CountryCanada
CityVancouver, BC
Period08/8/2008/8/25

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

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  • Cite this

    Kubo, T., Katayama, N., Karashima, A., & Nakao, M. (2008). The 3D position estimation of neurons in the hippocampus based on the multi-site multi-unit recordings with silicon tetrodes. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 (pp. 5021-5024). [4650341] (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology").