Tetranuclear titanium 7,7′-modified binaphtholate cluster as a novel chiral Lewis acid catalyst

Koichi Mikami, Makoto Ueki, Yousuke Matsumoto, Masahiro Terada

Research output: Contribution to journalArticlepeer-review

39 Citations (Scopus)

Abstract

Chiral tetranuclear Ti cluster, a cubic structure constituted of four Ti atoms and OHs, and six (R)-binaphthols (BINOL) bridged two Ti atoms as ligands, is shown to be a novel chiral Lewis acid catalyst for the [2+3] cycloaddition reaction with nitrones. The chiral Ti clusters with 7,7′-substituted (R)-BINOL ligands was synthesized to give enhanced enantiomeric excesses up to 78% ee.

Original languageEnglish
Pages (from-to)541-544
Number of pages4
JournalChirality
Volume13
Issue number9
DOIs
Publication statusPublished - 2001 Oct 20
Externally publishedYes

Keywords

  • 7,7′-substituted binaphthols
  • Asymmetric [2+3] cycloaddition reaction
  • Asymmetric catalyst
  • Chiral Lewis acid
  • Chiral titanium complex
  • Cluster

ASJC Scopus subject areas

  • Analytical Chemistry
  • Catalysis
  • Pharmacology
  • Drug Discovery
  • Spectroscopy
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Tetranuclear titanium 7,7′-modified binaphtholate cluster as a novel chiral Lewis acid catalyst'. Together they form a unique fingerprint.

Cite this