Testicular sperm extraction for non-obstructive azoospermia: results with conventional and microsurgical techniques

Kazutoshi Okubo, Keiji Ogura, Kentaro Ichioka, Naoki Terada, Yosuke Matsuta, Koji Yoshimura, Yoichi Arai, Tetsuro Honda, Kouichiro Umeoka, Takashi Nakahori, Akira Takahashi, You Umaoka

Research output: Contribution to journalReview articlepeer-review

16 Citations (Scopus)


Testicular sperm extraction (TESE) was performed on patients with non-obstructive azoospermia using the conventional or microdissection technique. First, conventional TESE was attempted on all patients. If the sperm was retrieved successfully, the TESE procedure was terminated. Microdissection TESE was indicated only for patients for whom the conventional sperm retrieval was unsuccessful. Sperm was successfully retrieved with conventional TESE from four (24%) of 17 patients with non-obstructive azoospermia. The remaining 13 patients underwent microdissection TESE and sperm was successfully retrieved from four of them. Application of the microdissection technique resulted in an improvement in sperm retrieval rates from 24% with conventional TESE to 48% when combined with the microdissection technique. None of the patients showed any acute or chronic complications after TESE. Intracytoplasmic sperm injection (ICSI) was performed on five of the eight patients with successful sperm retrieval and the partner of four of these patients became pregnant and progressed to delivery. These results indicate the usefulness of microdissection for improving the sperm retrieval rate in men with non-obstructive azoospermia.

Original languageEnglish
Pages (from-to)275-280
Number of pages6
JournalHinyokika kiyo. Acta urologica Japonica
Issue number5
Publication statusPublished - 2002 May

ASJC Scopus subject areas

  • Medicine(all)


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