Template-Assisted Preferential Formation of a Syn Photodimer in a Pyrophosphate-Induced Self-Assembly of a Thymine-Functionalized Isothiouronium Receptor

Yuichi Kato, Seiichi Nishizawa, Norio Teramae

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

(Matrix Presented) The effect of anion templation is investigated for the photodimerization of a thymine-functionalized isothiouronium receptor. The receptor forms a photodimer at the thymine moiety in methanol upon UV irradiation, while the isothiouronium moiety works as an oxoanion binding site via a two-point hydrogen-bonding motif. As compared to the case of a free receptor, the presence of pyrophosphate (PPi) resulted in the preferential formation of the syn-type photodimer, which would be desirable for recognizing the templated PPi.

Original languageEnglish
Pages (from-to)4407-4410
Number of pages4
JournalOrganic letters
Volume4
Issue number25
DOIs
Publication statusPublished - 2002 Dec 12

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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