TY - JOUR
T1 - Temperature-sensitive amorphous magnetic flakes for intratissue hyperthermia
AU - Matsuki, Hidetoshi
AU - Yanada, Toshiaki
AU - Sato, Tomoya
AU - Murakami, Koichi
AU - Minakawa, Sakae
PY - 1994/5/15
Y1 - 1994/5/15
N2 - For intratissue hyperthermia, we have developed capsules contained temperature-sensitive amorphous metal flakes, which can also release anticancer agents. By applying an alternating magnetic field, the amorphous flakes continue to generate heat until the temperature reaches the Curie point. The maximum temperature of the capsule is controlled automatically within an accuracy of ±0.5 °C. In animal experiments, the capsules generate sufficient heat or intratissue hyperthermia with the enhanced release of the anticancer agent. By using the capsules, richly vascularized tumours, such as kidney or liver cancers, are considered to be treated by a multifunctional procedure consisting of embolization therapy, hyperthermia and chemotherapy.
AB - For intratissue hyperthermia, we have developed capsules contained temperature-sensitive amorphous metal flakes, which can also release anticancer agents. By applying an alternating magnetic field, the amorphous flakes continue to generate heat until the temperature reaches the Curie point. The maximum temperature of the capsule is controlled automatically within an accuracy of ±0.5 °C. In animal experiments, the capsules generate sufficient heat or intratissue hyperthermia with the enhanced release of the anticancer agent. By using the capsules, richly vascularized tumours, such as kidney or liver cancers, are considered to be treated by a multifunctional procedure consisting of embolization therapy, hyperthermia and chemotherapy.
UR - http://www.scopus.com/inward/record.url?scp=0000391935&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0000391935&partnerID=8YFLogxK
U2 - 10.1016/0921-5093(94)90865-6
DO - 10.1016/0921-5093(94)90865-6
M3 - Article
AN - SCOPUS:0000391935
VL - 181-182
SP - 1366
EP - 1368
JO - Materials Science & Engineering A: Structural Materials: Properties, Microstructure and Processing
JF - Materials Science & Engineering A: Structural Materials: Properties, Microstructure and Processing
SN - 0921-5093
IS - C
ER -