Abstract
We prepared a novel antisense reagent comprising of oligodeoxynucleotides (ODNs) and a thermo-responsive polymer, poly(N-isopropylacrylamide) (PNIPAAm). The conjugate demonstrated stimuli-responsive regulation of gene expression via conformational change of the polymer chain.
Original language | English |
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Pages (from-to) | 986-987 |
Number of pages | 2 |
Journal | Chemistry Letters |
Volume | 32 |
Issue number | 11 |
DOIs | |
Publication status | Published - 2003 Nov 5 |
Externally published | Yes |
ASJC Scopus subject areas
- Chemistry(all)