Taxpropellane: A novel taxane with an unprecedented polycyclic skeleton from the needles of Taxus canadensis

Man Li Zhang, Mei Dong, Chang Hong Huo, Li Geng Li, Françoise Sauriol, Qing Wen Shi, Yu Cheng Gu, Hidefumi Makabe, Hiromasa Kiyota

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Taxpropellane, the first example of a taxane with an unprecedented 6/5/5/6/4/5-membered ring hexacyclic skeleton ([3.3.2]propellane), was isolated from the needles of Taxus canadensis. This compound would be derived from a normal 6/8/6 taxane by a [2+2] cycloaddition reaction between the 3,4- and 11,12-double bonds.

Original languageEnglish
Pages (from-to)5414-5417
Number of pages4
JournalEuropean Journal of Organic Chemistry
Issue number32
DOIs
Publication statusPublished - 2008 Nov 1

Keywords

  • Fused-ring systems
  • Propellanes
  • Structure elucidation
  • Terpenoids

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry

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    Zhang, M. L., Dong, M., Huo, C. H., Li, L. G., Sauriol, F., Shi, Q. W., Gu, Y. C., Makabe, H., & Kiyota, H. (2008). Taxpropellane: A novel taxane with an unprecedented polycyclic skeleton from the needles of Taxus canadensis. European Journal of Organic Chemistry, (32), 5414-5417. https://doi.org/10.1002/ejoc.200800587