Tandem-type PdII)-catalyzed oxidative Heck reaction/intramolecular C-H amidation sequence: A novel route to 4-aryl-2-quinolinones

Kiyofumi Inamoto; Junpei Kawasaki; Kou Hiroya; Yoshinori Kondo; Takayuki Doi

doi:10.1039/c2cc30600j

Tandem-type PdII)-catalyzed oxidative Heck reaction/intramolecular C-H amidation sequence: A novel route to 4-aryl-2-quinolinones

Kiyofumi Inamoto, Junpei Kawasaki, Kou Hiroya, Yoshinori Kondo, Takayuki Doi

PHA - Molecular Pharmaceutical Science

Research output: Contribution to journal › Article › peer-review

52 Citations (Scopus)

Abstract

A novel catalytic method for synthesizing 4-aryl-2-quinolinones is reported. The process involves two mechanistically independent, sequential PdII)-catalyzed reactions—the oxidative Heck reaction and the intramolecular C-H amidation—both of which smoothly proceed in the presence of a single catalytic system in a one-pot manner.

Original language	English
Pages (from-to)	4332-4334
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	36
DOIs	https://doi.org/10.1039/c2cc30600j
Publication status	Published - 2012 Apr 4

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c2cc30600j

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abstract = "A novel catalytic method for synthesizing 4-aryl-2-quinolinones is reported. The process involves two mechanistically independent, sequential PdII)-catalyzed reactions—the oxidative Heck reaction and the intramolecular C-H amidation—both of which smoothly proceed in the presence of a single catalytic system in a one-pot manner.",

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AU - Inamoto, Kiyofumi

AU - Kawasaki, Junpei

AU - Hiroya, Kou

AU - Kondo, Yoshinori

AU - Doi, Takayuki

PY - 2012/4/4

Y1 - 2012/4/4

N2 - A novel catalytic method for synthesizing 4-aryl-2-quinolinones is reported. The process involves two mechanistically independent, sequential PdII)-catalyzed reactions—the oxidative Heck reaction and the intramolecular C-H amidation—both of which smoothly proceed in the presence of a single catalytic system in a one-pot manner.

AB - A novel catalytic method for synthesizing 4-aryl-2-quinolinones is reported. The process involves two mechanistically independent, sequential PdII)-catalyzed reactions—the oxidative Heck reaction and the intramolecular C-H amidation—both of which smoothly proceed in the presence of a single catalytic system in a one-pot manner.

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Tandem-type PdII)-catalyzed oxidative Heck reaction/intramolecular C-H amidation sequence: A novel route to 4-aryl-2-quinolinones

Abstract

ASJC Scopus subject areas

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