Systemic Sarcoidosis Associated with Double Cancers of the Esophagus and Stomach

Osamu Usami, Masayuki Nara, Tsutomu Tamada, Tomomi Kitamuro, Masaiumi Tomaki, Yugo Ashino, Ko Onodera, Shukichi Miyazaki, Takuya Moriya, Toshio Hattori

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


To discriminate between sarcoidosis and sarcoid reaction in the lymphadenopathy of malignancy is sometimes clinically important. We describe a case of sarcoidosis associated with double cancers of the esophagus and stomach. A patient who six months previously was found to have early gastric cancer, was then found to have esophagus cancer. The chest radiography demonstrated bilateral hilar lymphadenopathy. Pathological analysis of the lymph nodes and lungs showed non-caseating epithelioid cell granuloma, revealing the existence of sarcoidosis. The findings suggest that the possibility of systemic sarcoidosis should be considered in cases with established malignancy and newly disclosed radiographic findings.

Original languageEnglish
Pages (from-to)2019-2022
Number of pages4
JournalInternal Medicine
Issue number24
Publication statusPublished - 2007


  • Granuloma
  • Lymphadenopathy
  • Sarcoid reaction

ASJC Scopus subject areas

  • Internal Medicine


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