Systematic evaluation and mechanistic investigation of antioxidant activity of fullerenols using β -Carotene bleaching assay

Hiroshi Ueno, Shizuka Yamakura, Riya S. Arastoo, Takumi Oshima, Ken Kokubo

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Antioxidant activity of hydroxylated fullerenes, so-called fullerenols, against lipid peroxyl radical was evaluated by β-carotene bleaching assay. All samples showed moderate to high antioxidant activity (%AOA), especially for COH)(70.1) and COH)(66.0) as compared with 8, 24, 26, and 36 hydroxylated ones (31.7-62.8). The detection of the possible products was conducted in the model reaction of both fullerenols and Cwith methyl linoleate by MALDI-TOF-MS. These results suggested that the two possible mechanisms, such as C-addition to double bonds and H-abstraction from -OH groups, are involved in the present radical scavenging reaction.

Original languageEnglish
Article number802596
JournalJournal of Nanomaterials
Volume2014
DOIs
Publication statusPublished - 2014

ASJC Scopus subject areas

  • Materials Science(all)

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