TY - JOUR
T1 - Systematic analysis of embryonic expression profiles of zinc finger genes in Ciona intestinalis
AU - Miwata, Kyoko
AU - Chiba, Takuto
AU - Horii, Reiko
AU - Yamada, Lixy
AU - Kubo, Atsushi
AU - Miyamura, Daisuke
AU - Satoh, Nori
AU - Satou, Yutaka
N1 - Funding Information:
This research was supported by a Grant-in-Aid from MEXT (the Ministry of Education, Science, Sports, Culture and Technology), Japan to Y.S. (13044001). This research was also supported in part by MEXT Grant-in-Aid to N.S. L.Y. was supported by a Predoctral Fellowship from the Japan Society for the Promotion of Science for Japanese Junior Scientists with Research Grant (15005628).
PY - 2006/4/15
Y1 - 2006/4/15
N2 - The recent decoding of a number of animal genomes has provided unprecedented information regarding evolution and gene structures, but this information must be supplemented with precise gene annotations and the temporal and spatial expression patterns of individual genes. In the present study, we systematically identified and characterized 566 zinc finger genes in the genome of Ciona intestinalis, an emerging model system for genome-wide studies of development and evolution. Of these genes, 356 genes encoded a potential transcription factor based on putative nucleic acid binding activity or domains of unknown function. We further examined the expression patterns of 225 genes during embryogenesis, and, when considered with a previous study [Imai, K.S., Hino, K., Yagi, K., Satoh, N., Satou, Y., 2004. Gene expression profiles of transcription factors and signaling molecules in the ascidian embryo: towards a comprehensive understanding of gene networks. Development 131, 4047-4058], we have characterized the developmental expression patterns of nearly 85% of the potential zinc finger-containing transcription factors. Overall, zinc finger genes are preferentially maternally expressed with little larval expression during development. The present study provides a valuable reference for genome-wide studies in this species and for future studies wishing to examine zinc finger gene expression patterns in other animals.
AB - The recent decoding of a number of animal genomes has provided unprecedented information regarding evolution and gene structures, but this information must be supplemented with precise gene annotations and the temporal and spatial expression patterns of individual genes. In the present study, we systematically identified and characterized 566 zinc finger genes in the genome of Ciona intestinalis, an emerging model system for genome-wide studies of development and evolution. Of these genes, 356 genes encoded a potential transcription factor based on putative nucleic acid binding activity or domains of unknown function. We further examined the expression patterns of 225 genes during embryogenesis, and, when considered with a previous study [Imai, K.S., Hino, K., Yagi, K., Satoh, N., Satou, Y., 2004. Gene expression profiles of transcription factors and signaling molecules in the ascidian embryo: towards a comprehensive understanding of gene networks. Development 131, 4047-4058], we have characterized the developmental expression patterns of nearly 85% of the potential zinc finger-containing transcription factors. Overall, zinc finger genes are preferentially maternally expressed with little larval expression during development. The present study provides a valuable reference for genome-wide studies in this species and for future studies wishing to examine zinc finger gene expression patterns in other animals.
KW - Ascidian
KW - Ciona intestinalis
KW - Expression profile
KW - Zinc finger
UR - http://www.scopus.com/inward/record.url?scp=33645939940&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33645939940&partnerID=8YFLogxK
U2 - 10.1016/j.ydbio.2006.01.024
DO - 10.1016/j.ydbio.2006.01.024
M3 - Article
C2 - 16519883
AN - SCOPUS:33645939940
VL - 292
SP - 546
EP - 554
JO - Developmental Biology
JF - Developmental Biology
SN - 0012-1606
IS - 2
ER -