Synthetic studies toward gambierol. Convergent synthesis of the octacyclic polyether core

Haruhiko Fuwa, Makoto Sasaki, Kazuo Tachibana

Research output: Contribution to journalArticlepeer-review

45 Citations (Scopus)

Abstract

(matrix presented) A convergent synthetic route to the octacyclic polyether core of gambierol, a marine polycyclic ether toxin, has been developed. The synthesis involves construction of two fragments representing the ABC and EFGH ring systems followed by their coupling via a B-alkyl Suzuki reaction.

Original languageEnglish
Pages (from-to)3549-3552
Number of pages4
JournalOrganic letters
Volume3
Issue number22
DOIs
Publication statusPublished - 2001 Nov 1

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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