Synthetic studies on optically active furofuran and diarylbutane lignans

Research output: Contribution to journalReview articlepeer-review

2 Citations (Scopus)

Abstract

Lignans are a large class of naturally occurring secondary metabolites which are widely spread within the plant kingdom. Their diverse structures and variety of biological activities have fascinated organic chemists. For synthesizing optically active lignans, we have developed the novel asymmetric dimerization of cinnamic acid derivatives, and applied it to the enantioselective syntheses of furofuran lignans (yangambin, sesamin, eudesmin, caruilignan A) and diarylbutane lignans (sauriols A and B). This review summarizes the methodology of our asymmetric dimerization of cinnamic acid derivatives, and efficient total syntheses of furofuran and diarylbutane lignans reported by our and other groups.

Original languageEnglish
Pages (from-to)1-8
Number of pages8
JournalBioscience, Biotechnology and Biochemistry
Volume82
Issue number1
DOIs
Publication statusPublished - 2018
Externally publishedYes

Keywords

  • Diarylbutane lignan
  • Electrochemical oxidation
  • Furofuran lignan
  • Oxidative dimerization
  • Synthesis

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Synthetic studies on optically active furofuran and diarylbutane lignans'. Together they form a unique fingerprint.

Cite this