Recent development of synthetic studies on novel marine alkaloids, haouamine A and B, is described. Haouamines have attracted considerable attention of synthetic chemists because of their unique structure and selective activity against human colon carcinoma cell line HT-29, however, only two groups have so far reported successful formation of their highly strained 3-aza--paracyclophane core. This review focuses on synthetic efforts to construct the core skeleton of haouamines reported by Baran and Wipf.
|Number of pages||2|
|Journal||Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry|
|Publication status||Published - 2008 Apr|
ASJC Scopus subject areas
- Organic Chemistry