Synthetic studies on haouamines with highly strained paracyclophane skeleton

Kentaro Okano

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Recent development of synthetic studies on novel marine alkaloids, haouamine A and B, is described. Haouamines have attracted considerable attention of synthetic chemists because of their unique structure and selective activity against human colon carcinoma cell line HT-29, however, only two groups have so far reported successful formation of their highly strained 3-aza-[7]-paracyclophane core. This review focuses on synthetic efforts to construct the core skeleton of haouamines reported by Baran and Wipf.

Original languageEnglish
Pages (from-to)387-388
Number of pages2
JournalYuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
Issue number4
Publication statusPublished - 2008 Apr
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry


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