A synthesis of the tetracyclic decalin part of azadirachtin in the naturally occurring form is described. The key reactions involve the Corey-Bakshi-Shibata (CBS) asymmetric reduction of the ketone, and an intramolecular Diels-Alder (IMDA) reaction.
- CBS asymmetric reduction
- Insect antifeedant
- Intramolecular Diels-Alder reaction
ASJC Scopus subject areas
- Organic Chemistry