Synthetic studies on altohyrtins (spongistatins): Synthesis of the C15- C28 (CD) spiroacetal portion

Takeshi Terauchi, Taro Terauchi, Ippei Sato, Tomoharu Tsukada, Naoki Kanoh, Masaya Nakata

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

The C15-C28 portion of altohyrtins (spongistatins) was prepared in a convergent manner from methyl (S)-3-hydroxy-2-methylpropionate, D-arabitol, and diacetone-D-glucose via dithiane couplings with epoxides as the key segment coupling process.

Original languageEnglish
Pages (from-to)2649-2653
Number of pages5
JournalTetrahedron Letters
Volume41
Issue number15
DOIs
Publication statusPublished - 2000 Apr 8

Keywords

  • Altohyrtins
  • Dithianes
  • Epoxides
  • Spiro compounds

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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