Abstract
The L-acid (C1-C18) fragment of pamamycin-593 and de-N-methylpamamycin-579, strong aerial mycelium-inducers of Streptomyces alboniger, was synthesized using a cis-selective iodoetherification and a nucleophilic addition of a cerium acetylide to an aldehyde as the key steps.
Original language | English |
---|---|
Pages (from-to) | 4955-4962 |
Number of pages | 8 |
Journal | European Journal of Organic Chemistry |
Issue number | 29 |
DOIs | |
Publication status | Published - 2008 Oct 1 |
Keywords
- Antibiotics
- Cerium acetylide
- Iodoetherification
- Pamamycins
- Synthesis design
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry