Stereoselective synthesis of the FGH ring fragment of ciguatoxin is described. The key steps in the present synthesis are an intramolecular radical cyclization to construct oxepane ring G and ring-closing metathesis reaction to construct hexahydrooxonin ring F.
|Number of pages||4|
|Publication status||Published - 1999 Feb 12|
- Radicals and radical reactions
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry