Synthesis of (-)-syringolides 1 and 2

Shigefumi Kuwahara, Masahiko Moriguchi, Kazuhiro Miyagawa, Masako Konno, Osamu Kodama

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)


The enantioselective synthesis of (-)-syringolides 1 and 2 which were isolated as specific elicitors produced by Pseudomonas syringae pv. tomato was accomplished in 11 steps from diethyl d tartrate. The specific rotations of synthetic samples were in good accord with those of the natural syringolides, and synthetic syringolide 2 showed almost the same biological activity as that of natural syringolide 2.

Original languageEnglish
Pages (from-to)8809-8814
Number of pages6
Issue number32
Publication statusPublished - 1995 Aug 7
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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