Synthesis of (-)-syringolides 1 and 2

Shigefumi Kuwahara, Masahiko Moriguchi, Kazuhiro Miyagawa, Masako Konno, Osamu Kodama

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

The enantioselective synthesis of (-)-syringolides 1 and 2 which were isolated as specific elicitors produced by Pseudomonas syringae pv. tomato was accomplished in 11 steps from diethyl d tartrate. The specific rotations of synthetic samples were in good accord with those of the natural syringolides, and synthetic syringolide 2 showed almost the same biological activity as that of natural syringolide 2.

Original languageEnglish
Pages (from-to)8809-8814
Number of pages6
JournalTetrahedron
Volume51
Issue number32
DOIs
Publication statusPublished - 1995 Aug 7
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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  • Cite this

    Kuwahara, S., Moriguchi, M., Miyagawa, K., Konno, M., & Kodama, O. (1995). Synthesis of (-)-syringolides 1 and 2. Tetrahedron, 51(32), 8809-8814. https://doi.org/10.1016/0040-4020(95)00488-T