Synthesis of rigidly-linked vancomycin dimers and their in vivo efficacy against resistant bacteria

Jun Lu, Osamu Yoshida, Sayaka Hayashi, Hirokazu Arimoto

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

A novel and efficient avenue for the preparation of dimeric vancomycins is described, and the dimers exhibited excellent antibacterial activities in the murine infection model.

Original languageEnglish
Pages (from-to)251-253
Number of pages3
JournalChemical Communications
Issue number3
DOIs
Publication statusPublished - 2007 Jan 11

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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