Synthesis of indenes by intramolecular morita-baylis-hillman reaction in aqueous media catalyzed by resin-supported proline

Kengo Akagawa, Seiji Sakamoto, Kazuaki Kudo

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

Novel synthesis of indene derivatives has been developed in an organocatalytic way. Although homogeneous proline showed low catalytic efficiency, resin-supported proline effectively catalyzed the intramolecular Morita-Baylis-Hillman reaction to afford the desired indenes.

Original languageEnglish
Pages (from-to)817-820
Number of pages4
JournalSynlett
Issue number6
DOIs
Publication statusPublished - 2011 Feb 24

Keywords

  • Morita-Baylis-Hillman reaction
  • aldehydes
  • annulation
  • proline
  • supported catalysis

ASJC Scopus subject areas

  • Organic Chemistry

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