Synthesis of Gd2O3 nanoparticles for MRI contrast agents

N. Sakai, L. Zhu, A. Kurokawa, H. Takeuchi, S. Yano, T. Yanoh, N. Wada, S. Taira, Y. Hosokai, A. Usui, Y. Machida, H. Saito, Y. Ichiyanagi

Research output: Contribution to journalConference article

26 Citations (Scopus)

Abstract

Gd2O3 nanoparticles were synthesized by using our original method for application as MRI contrast agents. The sample diameters were controlled in the range 18-66 nm by adjusting the annealing temperature between 773 and 1273 K in air or in an Ar atmosphere. Magnetization measurements were performed at 300 K, and the effective magnetic moment of each sample was calculated. They showed paramagnetism at 300 K and they had large effective magnetic moment μeff of 7.15-8.05 μB. MRI measurements were performed in 0.8 wt% agarose solution, and the Gd 2O3 nanoparticles were found to work as effective T 1-shortening MRI contrast agents.

Original languageEnglish
Article number012008
JournalJournal of Physics: Conference Series
Volume352
Issue number1
DOIs
Publication statusPublished - 2012
EventAsia-Pacific Interdisciplinary Research Conference 2011, AP-IRC 2011 - Aichi, Japan
Duration: 2011 Nov 172011 Nov 18

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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    Sakai, N., Zhu, L., Kurokawa, A., Takeuchi, H., Yano, S., Yanoh, T., Wada, N., Taira, S., Hosokai, Y., Usui, A., Machida, Y., Saito, H., & Ichiyanagi, Y. (2012). Synthesis of Gd2O3 nanoparticles for MRI contrast agents. Journal of Physics: Conference Series, 352(1), [012008]. https://doi.org/10.1088/1742-6596/352/1/012008