Synthesis of Fe doped hydroxyapatite by aqueous solution process

Mitsutaka Sato, Atsushi Nakahira

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Development of non toxic magnetic beads has been strongly desired to cure more effectively for patients having diseases such as cancer and osteosarcoma. In this study, Fe doped calcium phosphate powders were prepared by aqueous solution process. The crystal phase of obtained samples had a hydroxyapatite (HAp)-related structure with low crystallinity, and the crystallinity of samples decreased with increasing ratio of Fe (RFe). The crystallinity of samples improved by heat treatment more than 1073 K for 2 hours and α-Fe2O3 phase was generated as a second phase. The lattice parameter of HAp phase drastically changed at RFe = 1 mol% caused by the difference of ion radius between Ca ion and Fe ion, and there was a trend of that the a-axis shrinks and c-axis expands by further increment of RFe. The obtained powders had granular crystals with 10 nm in diameter. All samples showed paramagnetic property, and the maximum magnetization was 3 × 10-2 emu/g at RFc=5 mol%.

Original languageEnglish
Pages (from-to)529-532
Number of pages4
JournalFuntai Oyobi Fummatsu Yakin/Journal of the Japan Society of Powder and Powder Metallurgy
Volume57
Issue number7
DOIs
Publication statusPublished - 2010 Jul 1

Keywords

  • Aqueous solution process
  • Crystallinity
  • Drug delivery system
  • Fe-doped hydroxyapatite
  • Magnetic property

ASJC Scopus subject areas

  • Industrial and Manufacturing Engineering
  • Mechanical Engineering
  • Metals and Alloys
  • Materials Chemistry

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