Synthesis of (—)-ent-Altholactone, (+)-7a-epi-Altholactone, (—)-ent-Isoaltholactone and (—)-7a-epi-Isoaltholactone from 2,3-O-Cyclohexylidene-D-glyceraldehyde

Akira Hiratate, Hiromasa Kiyota, Takayuki Oritani

    Research output: Contribution to journalArticlepeer-review

    6 Citations (Scopus)

    Abstract

    Synthesis of the diastereomers of (+)-altholactone, an antitumor acetogenin from various Goniothalamus species, was achieved. Four isomers including 3a,7a-trans-fused analogs were synthesized from 2,3-O-cyclohexylidene-D-glyceraldehyde via twice separation of diastereomers.

    Original languageEnglish
    Pages (from-to)361-365
    Number of pages5
    JournalJournal of Pesticide Science
    Volume26
    Issue number4
    DOIs
    Publication statusPublished - 2001

    Keywords

    • altholactone
    • goniothalenol
    • isoaltholactone
    • total synthesis

    ASJC Scopus subject areas

    • Insect Science
    • Health, Toxicology and Mutagenesis

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