Synthesis of (—)-ent-Altholactone, (+)-7a-epi-Altholactone, (—)-ent-Isoaltholactone and (—)-7a-epi-Isoaltholactone from 2,3-O-Cyclohexylidene-D-glyceraldehyde

Akira Hiratate, Hiromasa Kiyota, Takayuki Oritani

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Synthesis of the diastereomers of (+)-altholactone, an antitumor acetogenin from various Goniothalamus species, was achieved. Four isomers including 3a,7a-trans-fused analogs were synthesized from 2,3-O-cyclohexylidene-D-glyceraldehyde via twice separation of diastereomers.

Original languageEnglish
Pages (from-to)361-365
Number of pages5
JournalJournal of Pesticide Science
Volume26
Issue number4
DOIs
Publication statusPublished - 2001 Jan 1

Keywords

  • altholactone
  • goniothalenol
  • isoaltholactone
  • total synthesis

ASJC Scopus subject areas

  • Insect Science
  • Health, Toxicology and Mutagenesis

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