Synthesis of bruceantin precursor: 15-deoxybruceolide

Makoto Sasaki, Tatsushi Murae, Takeyoshi Takahashi

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


A 15-deoxybruceolide, 11,12-di-O-acetyl-3-O-t-butyldimethylsilyl ether (3), was synthesized stereoselectively starting from the previously reported ABCE tetracyclic alcohol (5). The authentic sample of 3 was derived from naturally occurring brusatol (2).

Original languageEnglish
Pages (from-to)5953-5956
Number of pages4
JournalTetrahedron Letters
Issue number46
Publication statusPublished - 1988
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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