Synthesis of bis(indolyl)methanes catalyzed by acidic ionic liquid immobilized on silica (ILIS)

Hisahiro Hagiwara, Masayoshi Sekifuji, Takashi Hoshi, Kun Kyo, Chiaki Yokoyama

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

A new organocatalytic procedure for the synthesis of bis(indolyl)methanes with acidic ionic liquid immobilized on silica gel (ILIS-SO2Cl) has been developed. The reaction condition is applicable to a variety of aryl and aliphatic aldehydes and indoles. The mild nature of the reaction conditions showed that the acetoxy or TBDMS group in the aldehyde was maintained intact. The catalyst was reused four times in 93% average yield.

Original languageEnglish
Pages (from-to)1320-1322
Number of pages3
JournalSynlett
Issue number8
DOIs
Publication statusPublished - 2007 May 16

Keywords

  • Catalysis
  • Condensation
  • Indoles
  • Ionic liquids
  • Supported catalysis

ASJC Scopus subject areas

  • Organic Chemistry

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