Synthesis of a trisaccharide library by using a phenylsulfonate traceless linker on synphase crowns

Takashi Takahashi, Hitoshi Inoue, Yuichi Yamamura, Takayuki Doi

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

44 members are in the trisaccharide library synthesized by the method described here. Six differently protected glucoside building blocks were sulfonylated with 1, coupled to the solid support 2 (a crown compound) by Pd0-catalyzed carbonylative amidation, glycosylated twice, and cleaved from the sulfonate linker with four nucleophiles.

Original languageEnglish
Pages (from-to)3230-3233
Number of pages4
JournalAngewandte Chemie - International Edition
Volume40
Issue number17
DOIs
Publication statusPublished - 2001 Sep 3
Externally publishedYes

Keywords

  • Carbohydrates
  • Combinatorial chemistry
  • Solid-phase synthesis
  • Trisaccharides

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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