Synthesis of 17-[18F]fluoro-5-methylheptadecanoic acid

Toshihiro Takahashi, Tatsuo Ido, Ren Iwata

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

5-Methyl-branched fatty acid, which was designed for less hindrance by the methyl group in heart uptake as compared with the 3-methyl-branched fatty acid, was labeled with fluorine-18 at the ω-position. The total time of synthesis, including HPLC purification and emulsification was 85-100 min from the start of reactive 18F- production. The decay-corrected isolated yields of 17-[18F]fluoro-5-methyl-heptadecanoic acid after emulsification were 10-17% and the radiochemical purities were >97%.

Original languageEnglish
Pages (from-to)822-824
Number of pages3
JournalInternational Journal of Radiation Applications and Instrumentation. Part
Volume43
Issue number6
DOIs
Publication statusPublished - 1992 Jun
Externally publishedYes

ASJC Scopus subject areas

  • Radiation
  • Engineering(all)

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