5-Methyl-branched fatty acid, which was designed for less hindrance by the methyl group in heart uptake as compared with the 3-methyl-branched fatty acid, was labeled with fluorine-18 at the ω-position. The total time of synthesis, including HPLC purification and emulsification was 85-100 min from the start of reactive 18F- production. The decay-corrected isolated yields of 17-[18F]fluoro-5-methyl-heptadecanoic acid after emulsification were 10-17% and the radiochemical purities were >97%.
|Number of pages||3|
|Journal||International Journal of Radiation Applications and Instrumentation. Part|
|Publication status||Published - 1992 Jun|
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