Synthesis and transfection capability of multi-functionalized fullerene polyamine

Hiroyuki Isobe, Naoki Tomita, Shigeki Jinno, Hiroto Okayama, Eiichi Nakamura

    Research output: Contribution to journalArticlepeer-review

    31 Citations (Scopus)

    Abstract

    A new fullerene transfection reagent bearing multiple-functional groups has been synthesized by diastereoselective double cycloaddition reaction. The highly oxygenated reagent transfers extra-cellular DNA into mammalian cells with the efficiency comparable to that of a nor-analogue.

    Original languageEnglish
    Pages (from-to)1214-1215
    Number of pages2
    JournalChemistry Letters
    Issue number12
    DOIs
    Publication statusPublished - 2001 Jan 1

    ASJC Scopus subject areas

    • Chemistry(all)

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