Synthesis and stereochemical confirmation of the HI/JK ring system of prymnesins, potent hemolytic and ichthyotoxic glycoside toxins isolated from the red tide alga

Makoto Sasaki, Takeshi Shida, Kazuo Tachibana

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Stereocontrolled synthesis of the HI/JK ring model of the prymnesins, glyosidic toxins isolated from the red tide phytoflagellate Prymnesium parvum, is described. Comparison of its 1H and 13C NMR data with those of the natural toxins established the earlier stereochemical assignments.

Original languageEnglish
Pages (from-to)5725-5728
Number of pages4
JournalTetrahedron Letters
Volume42
Issue number33
DOIs
Publication statusPublished - 2001 Aug 13

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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