Synthesis and spectroscopic properties of new phthalocyanine complexes with potentially combined photodynamic activity and cytotoxicity for photodynamic therapy

V. N. Nemykin, V. M. Mytsyk, S. V. Volkov, N. Kobayashi

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The reaction of zinc tetrakis(3-pyridyloxy)phthalocyanine (1) with NH4[PtNH3Cl3] leads to zinc tetrakis(cis-[3-oxypyridyl]-N]amminedichloroplatinum(II))phthalocyanine (2), while the reaction of 1 with cis-Pt (DMSO)2Cl2 or 2 with DMSO forms zinc tetrakis(cis-[(3-oxypyridyl)-N]dichloro[sulfinylbis(methane)-S]platinum(II))p hthalocyanine (3). The new phthalocyanines 2 and 3, with potentially combined photodynamic activity and cytotoxicity, have been characterized by means of electronic, 1H NMR and IR spectroscopies. Copyright (C) 2000 John Wiley and Sons, Ltd.

Original languageEnglish
Pages (from-to)551-554
Number of pages4
JournalJournal of Porphyrins and Phthalocyanines
Volume4
Issue number5
DOIs
Publication statusPublished - 2000 Jan 1

Keywords

  • Heterometallic polynuclear phthalocyanines
  • Photodynamic therapy
  • Platinum

ASJC Scopus subject areas

  • Chemistry(all)

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