Synthesis and reactions of 4-tributylstannyl-3-methylisoxazole

Daishi Uchiyama; Makoto Yabe; Hiroshi Kameyama; Takao Sakamoto; Yoshinori Kondo; Hiroshi Yamanaka

doi:10.3987/com-96-7489

Synthesis and reactions of 4-tributylstannyl-3-methylisoxazole

Daishi Uchiyama, Makoto Yabe, Hiroshi Kameyama, Takao Sakamoto, Yoshinori Kondo, Hiroshi Yamanaka

PHA - Molecular Pharmaceutical Science

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

1,3-Dipolar cycloaddition reaction of bis(tributylstannyl)acetylene with nitrile oxides, followed by treatment with aqueous ammonia in ethanol in a sealed tube gave 4-tributylstannyl-3-methylisoxazole. The palladium catalyzed cross coupling reaction of the isoxazole with 2-iodonitrobenzene, followed by reductive cyclization afforded 3-acetylindole.

Original language	English
Pages (from-to)	1301-1304
Number of pages	4
Journal	Heterocycles
Volume	43
Issue number	6
DOIs	https://doi.org/10.3987/com-96-7489
Publication status	Published - 1996

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

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title = "Synthesis and reactions of 4-tributylstannyl-3-methylisoxazole",

abstract = "1,3-Dipolar cycloaddition reaction of bis(tributylstannyl)acetylene with nitrile oxides, followed by treatment with aqueous ammonia in ethanol in a sealed tube gave 4-tributylstannyl-3-methylisoxazole. The palladium catalyzed cross coupling reaction of the isoxazole with 2-iodonitrobenzene, followed by reductive cyclization afforded 3-acetylindole.",

author = "Daishi Uchiyama and Makoto Yabe and Hiroshi Kameyama and Takao Sakamoto and Yoshinori Kondo and Hiroshi Yamanaka",

year = "1996",

doi = "10.3987/com-96-7489",

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publisher = "Japan Institute of Heterocyclic Chemistry",

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T1 - Synthesis and reactions of 4-tributylstannyl-3-methylisoxazole

AU - Uchiyama, Daishi

AU - Yabe, Makoto

AU - Kameyama, Hiroshi

AU - Sakamoto, Takao

AU - Kondo, Yoshinori

AU - Yamanaka, Hiroshi

PY - 1996

Y1 - 1996

N2 - 1,3-Dipolar cycloaddition reaction of bis(tributylstannyl)acetylene with nitrile oxides, followed by treatment with aqueous ammonia in ethanol in a sealed tube gave 4-tributylstannyl-3-methylisoxazole. The palladium catalyzed cross coupling reaction of the isoxazole with 2-iodonitrobenzene, followed by reductive cyclization afforded 3-acetylindole.

AB - 1,3-Dipolar cycloaddition reaction of bis(tributylstannyl)acetylene with nitrile oxides, followed by treatment with aqueous ammonia in ethanol in a sealed tube gave 4-tributylstannyl-3-methylisoxazole. The palladium catalyzed cross coupling reaction of the isoxazole with 2-iodonitrobenzene, followed by reductive cyclization afforded 3-acetylindole.

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U2 - 10.3987/com-96-7489

DO - 10.3987/com-96-7489

M3 - Article

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JO - Heterocycles

JF - Heterocycles

SN - 0385-5414

IS - 6

ER -

Synthesis and reactions of 4-tributylstannyl-3-methylisoxazole

Abstract

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