TY - JOUR
T1 - Synthesis and Interaction Studies on Water Soluble Nucleic Acid Analogs
T2 - Poly(L-lysine) Derivatives Containing Thymine and Hypoxanthine*
AU - Wada, Takehiko
AU - Inaki, Yoshiaki
AU - Takemoto, Kiichi
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1992/1
Y1 - 1992/1
N2 - Nucleic acid analogs were prepared by grafting nucleic acid base derivatives containing hydroxy groups onto poly(L-lysine). The polymers con tained about 70 unit% of the nucleic acid bases, and were easily soluble in water at neutral pH value. Conformational changes and polymer complexes with polynucleotides [Poly(A) and Poly(C)] were observed with specific base- base interactions in aqueous solution.
AB - Nucleic acid analogs were prepared by grafting nucleic acid base derivatives containing hydroxy groups onto poly(L-lysine). The polymers con tained about 70 unit% of the nucleic acid bases, and were easily soluble in water at neutral pH value. Conformational changes and polymer complexes with polynucleotides [Poly(A) and Poly(C)] were observed with specific base- base interactions in aqueous solution.
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U2 - 10.1177/088391159200700104
DO - 10.1177/088391159200700104
M3 - Article
AN - SCOPUS:0026589287
VL - 7
SP - 25
EP - 38
JO - Journal of Bioactive and Compatible Polymers
JF - Journal of Bioactive and Compatible Polymers
SN - 0883-9115
IS - 1
ER -