Abstract
Nucleic acid analogs were prepared by grafting nucleic acid base derivatives containing hydroxy groups onto poly(L-lysine). The polymers con tained about 70 unit% of the nucleic acid bases, and were easily soluble in water at neutral pH value. Conformational changes and polymer complexes with polynucleotides [Poly(A) and Poly(C)] were observed with specific base- base interactions in aqueous solution.
Original language | English |
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Pages (from-to) | 25-38 |
Number of pages | 14 |
Journal | Journal of Bioactive and Compatible Polymers |
Volume | 7 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1992 Jan |
Externally published | Yes |
ASJC Scopus subject areas
- Bioengineering
- Biomaterials
- Polymers and Plastics
- Materials Chemistry