Synthesis and interaction studies of watersoluble nucleic acid analogs containing serine as a spacer.

T. Wada, N. Masumi, E. Mochizuki, Y. Inaki, K. Takemoto

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Watersoluble nucleic acid analogs containing L- or D-serine as a spacer were synthesized. Thymine was used as nucleic acid bases of these analogs. The base contents of these analogs were 93-94%. These analogs were found to form stable polymer complexes with Poly A or DNA by specific base-base interaction, which were observed from hypochromicity of UV spectra. In both cases, the maximum hypochromicity values of PEI-L-Ser-Thy were higher than that of PEI-D-Ser-Thy.

Original languageEnglish
Pages (from-to)115-116
Number of pages2
JournalNucleic acids symposium series
Issue number27
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Medicine(all)

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