Synthesis and confirmation of the structures of polonicumtoxins A, B and C

Mari Yotsu-Yamashita, Takeshi Yasumoto, Viresh H. Rawal

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Total syntheses of polonicumtoxins A (1), B (2), and C (3) have been completed. The key step of the syntheses involves an aza-Wittig reaction for the construction of the cyclic ketimine. The synthetic compounds were found to be identical in all respects with the natural products, thus confirming their assigned structures.

Original languageEnglish
Pages (from-to)79-93
Number of pages15
JournalHeterocycles
Volume48
Issue number1
Publication statusPublished - 1998 Dec 1

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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