Synthesis and biological evaluation of aspergillide a/neopeltolide chimeras

Haruhiko Fuwa, Kenkichi Noto, Masato Kawakami, Makoto Sasaki

    Research output: Contribution to journalArticlepeer-review

    5 Citations (Scopus)

    Abstract

    In this study, stereoisomeric aspergillide A/neopeltolide chimeras were synthesized in a parallel manner, and their antiproliferative activity was evaluated to demonstrate the potential utility of the 14-membered macrolactone structure embedded with a tetrahydropyran substructure as a template for developing natural product-like antiproliferative agents.

    Original languageEnglish
    Pages (from-to)1020-1022
    Number of pages3
    JournalChemistry Letters
    Volume42
    Issue number9
    DOIs
    Publication statusPublished - 2013

    ASJC Scopus subject areas

    • Chemistry(all)

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