Symptomatic intradural adrenal adenoma of the spinal nerve root: Report of two cases

Andrew Mitchell, Bernd W. Scheithauer, Hironobu Sasano, Elizabeth W. Hubbard, Michael J. Ebersold

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)


THE SECOND AND THIRD cases of an adrenal adenoma involving the intraspinal space, a rare location for a lesion that occurs rather commonly at a variety of extraneural sites, are reported. The first patient, a 16-year-old girl with a 3-month history of radicular pain, was found to have an intradural, extramedullary mass arising on a spinal nerve root. Its resection resulted in cure. The second patient, a 63-year-old woman with a 10-month history of low back pain with radiation to both lower extremities, had a similar mass arising from one of the nerve roots of the cauda equina. In both cases, ultrastructural examination of these demarcated, oncocytic, lipid-rich lesions demonstrated abundant smooth endoplasmic reticulum and mitochondria with tubular cristae. The presence of steroidogenic enzymes was noted on immunohistochemical examination. The literature is reviewed, as is the differential diagnosis of these rare lesions.

Original languageEnglish
Pages (from-to)658-662
Number of pages5
Issue number4
Publication statusPublished - 1993 Apr
Externally publishedYes


  • Adrenal rest
  • Immunocytology
  • Nerve
  • Oncocytoma
  • Ultrastructure

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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