Switching Modulation for Protein Labeling with Activatable Fluorescent Probes

Kalyan K. Sadhu, Shin Mizukami, Yuichiro Hori, Kazuya Kikuchi

Research output: Contribution to journalShort surveypeer-review

9 Citations (Scopus)

Abstract

Fluorogenic protein-labeling techniques have been successfully used in live-cell imaging. Fluorescence derived from specific labeling can monitor the localization of proteins. Newly developed chemical techniques have addressed such specific incorporation of probes in the physiological environment. We conclude that some recent promising switching techniques should provide further molecular functional exploitation in vivo.

Original languageEnglish
Pages (from-to)1299-1308
Number of pages10
JournalChemBioChem
Volume12
Issue number9
DOIs
Publication statusPublished - 2011 Jun 14
Externally publishedYes

Keywords

  • Biotechnology
  • Dyes
  • Fluorescence spectroscopy
  • Fluorescent probes
  • Protein labeling

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Organic Chemistry

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