Survey of Acinetobacter baumannii Isolates in a NICU at a General Hospital

Hidenari Takane, Shigeru Fujimura, Yoshihisa Nakano, Katsuhiro Fuse, Kazunori Gomi, Toshiaki Kikuchi, Toshihiro Nukiwa, Akira Watanabe

Research output: Contribution to journalArticlepeer-review

Abstract

Ventilator-associated pneumonia caused by multidrug-resistant Acinetobacter baumannii in intensive care units has become a problem worldwide. In Japan, few reports of antimicrobial susceptibility or nosocomial infection have involved A. baumannii. We confirmed A. baumannii nosocomial infection in a neonatal intensive care unit (NICU) of general hospital A in the Tohoku region from May 2008 to February 2009, so spreading of infection and environmental contamination were examined. Antimicrobial susceptibilities of 51 clinical isolates in NICU and 2 environmental isolates, thermometer and knob, in March 2009 were determined by the micro-dilution method. Furthermore, the genotype of these strains was determined using the AP-PCR and ERIC-PCR methods. During this period, three nosocomial infections (June, September, February) caused by A. baumannii were confirmed. In this study, there was no isolation of multidrug-resistant strains. The genotype of each A. baumannii strain in these nosocomial infections was different. The genotype of the A. baumannii strain isolated from the thermometer which only patient A had used was identified with that of the nosocomial infection in February. These results showed the possibility that several A. baumannii strains were transmitted through staff of the NICU. A. baumannii surveillance may be important to prevent nosocomial infection in the NICU.

Original languageEnglish
Pages (from-to)242-246
Number of pages5
JournalJapanese Journal of Environmental Infections
Volume25
Issue number4
DOIs
Publication statusPublished - 2010

Keywords

  • A. baumannii
  • NICU
  • antimicrobial resistance
  • nosocomial infection

ASJC Scopus subject areas

  • Epidemiology

Fingerprint Dive into the research topics of 'Survey of Acinetobacter baumannii Isolates in a NICU at a General Hospital'. Together they form a unique fingerprint.

Cite this