Surgical outcomes of laparoscopic adrenalectomy for patients with Cushing's and subclinical Cushing's syndrome: A single center experience

Minoru Miyazato, Shigeto Ishidoya, Fumitoshi Satoh, Ryo Morimoto, Yasuhiro Kaiho, Shigeyuki Yamada, Akihiro Ito, Haruo Nakagawa, Sadayoshi Ito, Yoichi Arai

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Objective We retrospectively examined the outcome of patients who underwent laparoscopic adrenalectomy for Cushing's/subclinical Cushing's syndrome in our single institute. Patients and methods Between 1994 and 2008, a total of 114 patients (29 males and 85 females, median age 54 years) with adrenal Cushing's/subclinical Cushing's syndrome were studied. We compared the outcome of patients who underwent laparoscopic adrenalectomy between intraperitoneal and retroperitoneal approaches. Surgical complications were graded according to the Clavien grading system. We also examined the long-term results of subclinical Cushing's syndrome after laparoscopic adrenalectomy. Results Laparoscopic surgical outcome did not differ significantly between patients with Cushing's syndrome and those with subclinical Cushing's syndrome. Patients who underwent laparoscopic intraperitoneal adrenalectomy had longer operative time than those who received retroperitoneal adrenalectomy (188.2 min vs. 160.9 min). However, operative blood loss and surgical complications were similar between both approaches. There were no complications of Clavien grade III or higher in either intraperitoneal or retroperitoneal approach. We confirmed the improvement of hypertension and glucose tolerance in patients with subclinical Cushing's syndrome after laparoscopic adrenalectomy. Conclusions Laparoscopic adrenalectomy for adrenal Cushing's/subclinical Cushing's syndrome is safe and feasible in either intraperitoneal or retroperitoneal approach. The use of the Clavien grading system for reporting complications in the laparoscopic adrenalectomy is encouraged for a valuable quality assessment.

Original languageEnglish
Pages (from-to)975-981
Number of pages7
JournalInternational Urology and Nephrology
Volume43
Issue number4
DOIs
Publication statusPublished - 2011 Dec 1

Keywords

  • Clavien grading system
  • Cushing's syndrome
  • Laparoscopic adrenalectomy
  • Subclinical Cushing's syndrome

ASJC Scopus subject areas

  • Nephrology
  • Urology

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