Super helix formation of actin filaments in an in vitro motile system

Yuichiro Tanaka, Akihiko Ishijima, Shin'ichi Ishiwata

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)


Muscle contraction results from relative sliding of actin and myosin filaments. However, the possibility that actin filaments twist or rotate during sliding has not yet been experimentally investigated. We found that a super helix of an actin filament is formed in an in vitro motile system. This fact suggests that an actin filament twists and rotates due to a torque component of a sliding force generated at cross-bridges.

Original languageEnglish
Pages (from-to)94-98
Number of pages5
JournalBiochimica et Biophysica Acta (BBA)/Protein Structure and Molecular
Issue number1
Publication statusPublished - 1992 Sep 4


  • Actin filament
  • Muscle contraction
  • Mutile system
  • Super helix formation

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology

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