Sugar-sensitive thin films composed of concanavalin A and glycogen

Katsuhiko Sato, Yoko Imoto, Jun Sugama, Shunsuke Seki, Hiroyuki Inoue, Tsuyoshi Odagiri, Jun Ichi Anzai

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)

Abstract

Sugar-sensitive thin films were prepared by a layer-by-layer deposition of concanavalin A (Con A) and glycogen on the surface of a quartz slide and their sugar-induced decomposition was studied. The Con A/glycogen multilayer films can be decomposed by exposing them to sugar solutions (D-glucose, D-mannose, methyl-α-D-glucose and methyl-α-D-mannose), as a result of displacement of sugar residues of glycogen from the binding sites of Con A by the free sugar added in the solution. The rate of decomposition significantly depended on the type of sugar and its concentration.

Original languageEnglish
Pages (from-to)1247-1248
Number of pages2
Journalanalytical sciences
Volume20
Issue number9
DOIs
Publication statusPublished - 2004 Sep
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry

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